Alexion Pharmceuticals - Executive Director Resume Example

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Zoe Jenkins
XXX XXXXXXXXX XXXX, Southport, CT 06890
Profile: Over thirty years of broad-based experience encompassing clinical medicine, drug development, regulatory affairs, basic and clinical biomedical research, and executive leadership within the biotechnology industry
Executive Director, Strategic Evaluation Jun 2011Present Alexion Pharmceuticals, Inc Cheshire, CT

Leading a four member Search and Evaluation team with the mission to:

  • Drive the identification and evaluation of external innovation across the pharmaceutical, biotechnology and academic arenas.

  • Pursue in-licensing and/or M&A opportunities encompassing enabling technologies, drug discovery platforms, and high value drug candidates diversified by stages of development, therapeutic modalities, and clinical areas

  • Execute rigorous due-diligence assessments that enable thoroughly-informed decision-making on those collaborations and alliances that will best advance the company's strategic priorities

  • Develop and maintain business relationships with key external collaborators in the biotechnology, pharmaceutical and venture communities

  • Enhance Alexion's pipeline and competitive position in relation to its industry peers

Founder, President and Chief Executive Officer, Director Jun 2006May 2011 Immune Tolerance Institute, Inc
  • ITI was an independent, non-profit 501(c)(3) corporation founded in 2006 in partnership with the University of California, San Francisco (UCSF), to translate scientific discovery into personalized medicines for the millions of people afflicted by diseases of the immune system.
  • ITI's programs were designed to develop novel immune biomarkers to more effectively guide new drug development and match patients with therapies that provide them the greatest benefit Milestones achieved included: i. Research Services Agreement established with UCSF including 11.5 million of funding through FY2012 ii. Recruitment of experienced management and scientific teams iii. Established diagnostic technology platforms in cellular and genetic analysis (polychromatic flow cytometry and quantitative gene expression) iv. Forged partnerships with the Immune Tolerance Network (ITN), TrialNet, Bristol Myers Squibb, David H Murdock Research Institute (DHMRI), and LabCorp, Inc.
  •  In January 2011 ITI was acquired by the DHMRI.
President, Chief Executive Officer, Director Sep 2000Mar 2006 CGI Pharmaceuticals, Inc Branford, CT

Developed business strategy to leverage proprietary core technology platforms for kinase inhibitor drug discovery and development programs with broad clinical and commercial potential in cancer and autoimmune/inflammatory diseases

Raised $62MM in three rounds of private equity financing, attracting top tier venture firms and establishing a broad investor base of 11 investor groups

Directed corporate and business development activities, initiating and leading discussions with select partners on company's drug development programs; identified and evaluated strategic business opportunities including products for in-licensing

Established 5 collaborations with top-tier pharmaceutical and biotechnology companies (Lilly, Pfizer, Schering AG, Serono, Affymetrix)

Recruited experienced executive management team

Established relationships with multiple healthcare investment banking groups, made presentations at numerous healthcare and biotechnology investor conferences, providing the groundwork for future transactions (IPO or M&A)


(In October 2006, CGI entered into an exclusive global collaboration agreement with Genentech to discover, develop, manufacture and commercialize CGl's Btk kinase inhibitor for the potential treatment of B cell malignancy and autoimmune diseases; in June, 2010 CGI was acquired by Gilead Sciences, Inc.)

Jun 2001
Director of Immunology; Vice President, lmmunobiology; Senior Vice President and Chief Scientific Officer Jan 1993Sep 2000 Alexion Pharmaceuticals, Inc New Haven, CT
  • Directed multiple facets of corporate activity, from discovery research to early stage clinical development; responsible for the establishment of major technology platforms and for discovery and development of novel biologics
  • Responsibilities included: identification of clinical disease targets and direction of drug discovery and development programs; generation of lead product candidates and demonstration of preclinical proof-of-concept in multiple disease models, including Alexion's first in class anti-C5 mAb, Eculizumab; technology evaluation and in-licensing/acquisition, obtaining exclusive worldwide license to key technology from the National Institutes of Health in the area of immune tolerance.
  • Management of the Collaborative Research and Development Agreement (CRADA) with the NIH as well as the internal R&D effort in this area
  •  Frequent presentation of company programs to the scientific, pharmaceutical, and investment communities, including presentations as an invited speaker at scientific, medical, and biotechnology conferences, and to potential pharmaceutical partners
  • Co-inventor on 10 patents and patent applications
  • Participant in discussions with the FDA regarding clinical development programs
  • Member of senior management team conducting successful IPO in 1996 .
Senior Investigator Jan 1990Jan 1993 National Cancer Institute Bethesda, MD
Senior Fellow Jan 1987Jan 1990 Center for Biologics, Food and Drug Administration Bethesda, MD
Medical Oncology Fellow and Senior Investigator Jun 1981Jan 1987 National Cancer Institute Besthesda, MD
Clinical Associate Jun 1977Jun 1981 National Institute of Allergy and Infectious Diseases Besthesda , MD
Internal Medicine Resident Jun 1975Jun 1977 University of Chicago Hospitals and Clinics Chicago, IL
M.D Jun 1975 University of Pennsylvania Philadelphia, PA
Bachelor of Arts : summa cum laude Jun 1971 Amherst College Amherst, MA

Alpha Omega Alpha, 1975

American Society for Clinical Investigation, 1991

NIH Award of Merit, 1992

Appointed to the Medical Alumni Advisory Council, University of Pennsylvania School of Medicine, 2006, Co-Chair, 2010-2013

Appointed, Campaign Leadership Cabinet, University of Pennsylvania School of Medicine, 2013-present

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Executive Director FROM Southport , Connecticut RESUME

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School Attended
University of Pennsylvania